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fluoxetine
Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), has been a cornerstone in psychopharmacology since its approval. Initially developed as an antidepressant, its applications have expanded significantly over decades of clinical use. The molecule’s unique pharmacokinetic profile—notably its active metabolite norfluoxetine with an extended half-life—creates both therapeutic advantages and clinical challenges that every prescriber needs to understand intimately. Fluoxetine: Comprehensive Management of Depression and Related Disorders - Evidence-Based Review 1. Introduction: What is Fluoxetine?
abilify
Aripiprazole represents one of the most fascinating psychopharmacological developments of the past two decades - a third-generation antipsychotic that functions as a partial dopamine agonist rather than a pure antagonist. When I first encountered this mechanism during my residency, the concept seemed almost paradoxical: how could a medication simultaneously treat psychosis while having potential antidepressant properties? The answer lies in its unique receptor profile that allows it to act as a functional stabilizer rather than simply blocking or stimulating neurotransmitter systems.
Anafranil: Potent Serotonergic Modulation for Obsessive-Compulsive Disorder - Evidence-Based Review
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asendin
Let me walk you through our experience with Asendin - the amoxapine formulation that’s been quietly revolutionizing how we approach certain depression subtypes. When it first hit our formulary back in 2018, honestly, most of us were skeptical. Another tricyclic derivative? Really? But Dr. Chen in psych kept pushing us to look at the receptor profile differently. ## What is Asendin? Its Role in Modern Medicine Asendin (amoxapine) represents what happens when you take the classic tricyclic antidepressant structure and actually optimize it for modern practice.
bentyl
Bentyl, known generically as dicyclomine hydrochloride, is an anticholinergic/antispasmodic agent primarily used to treat symptoms of irritable bowel syndrome (IBS). It works by relaxing the smooth muscles in the gut, reducing cramping and spasms. Available in tablet and liquid forms, it’s been a staple in gastroenterology for decades, though its use requires careful patient selection due to its side effect profile. Bentyl: Effective Symptom Relief for Irritable Bowel Syndrome - Evidence-Based Review 1.
Bupropion: Effective Depression and Smoking Cessation Treatment - Evidence-Based Review
Bupropion is an atypical antidepressant belonging to the aminoketone class, structurally distinct from SSRIs and TCAs. Initially developed in 1969 and approved by the FDA in 1985, it functions primarily as a norepinephrine-dopamine reuptake inhibitor (NDRI) with minimal serotonergic activity. This unique mechanism underlies its clinical applications beyond depression, including smoking cessation and off-label uses for ADHD and sexual dysfunction. Unlike many antidepressants, bupropion is associated with weight neutrality or modest weight loss and lacks sexual side effects, making it particularly valuable for specific patient populations.
bystolic
Bystolic represents one of the more elegant beta-blockers in our modern cardiovascular arsenal, a selective beta-1 adrenergic receptor blocker with the chemical name nebivolol. Unlike its predecessors, it combines beta-blockade with a unique nitric oxide-mediated vasodilatory effect, which fundamentally changes its side effect profile and therapeutic applications. When I first encountered Bystolic during my cardiology fellowship, we were still grappling with the fatigue and bronchospasm concerns of older agents like propranolol.
celexa
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Coreg: Comprehensive Heart Failure and Hypertension Management - Evidence-Based Review
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